GenerpoB
Protein ChangeQ513L
Nucleotide ChangeC513T
Validation StatusConfirmed2+ DBs
Databases
ResFinderReslit
Overview
- Mechanism
- Target modification
- Resistance To
- rifampin|rifabutin|rifapentine, rifampin, Rifampicin
- Organisms
- Escherichia coli, Mycobacterium tuberculosis
- Papers
- 3
Paper Information3
1
Cross-resistance of Escherichia coli RNA polymerases conferring rifampin resistance to different antibiotics.
Mutations in the rpoB gene encoding the beta subunit of RNA polymerase confer resistance to rifampin and related antibiotics.
Mutation Information
- Protein Change
- Q513L
- Organisms
- Escherichia coli
- Confers Resistance To
- rifampin|rifabutin|rifapentine
- Source Database
- Reslit
2
Genetic evaluation of relationship between mutations in rpoB and resistance of Mycobacterium tuberculosis to rifampin.
Some mutations in the rpoB gene can reveal drug-resistant phenotype only in a specific genetic background of the host.
Mutation Information
- Protein Change
- Q513L
- Nucleotide Change
- C513T
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- rifampin
- Source Database
- Reslit
3
Mapping and sequencing of mutations in the Escherichia coli rpoB gene that lead to rifampicin resistance.
Mutation Information
- Protein Change
- Q513L
- Organisms
- Escherichia coli
- Confers Resistance To
- Rifampicin
- Effect on Function
- Target modification
- Source Database
- ResFinder
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