Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Molecular dynamics simulation studies of the wild-type, I21V, and I16T mutants of isoniazid-resistant Mycobacterium tuberculosis enoyl reductase (InhA) in complex with NADH: toward the understanding of NADH-InhA different affinities.
Mutations in the glycine-rich loop of InhA reduce NADH affinity, contributing to isoniazid resistance.
Molecular Dynamics Assisted Mechanistic Study of Isoniazid-Resistance against Mycobacterium tuberculosis InhA.
Mutations in InhA reduce NADH binding affinity, leading to isoniazid resistance.
Artificial Intelligence and Machine learning based prediction of resistant and susceptible mutations in Mycobacterium tuberculosis.
Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates.
Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid; CARD accession: CARD:3003393
Tuberculosis drug resistance mutation database.
The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis.
No comments yet. Be the first to comment!
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research