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Browse Mutations mshA1242del

GenemshA

mycothiol synthase

Nucleotide Change1242del

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: Loss of function
Resistance To: Ethionamide
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

1

Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.

PMID 18651841 · 2008

Mutations in mshA lead to ethionamide resistance.

Mutation Information

mshA: c.1242del

Nucleotide Change: 1242del
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Ethionamide

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

Loss of function

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research