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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations mtrRG45D

GenemtrR

Protein ChangeG45D

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: disrupts the DNA-binding domain of the MtrR repressor
Resistance To: ceftriaxone|cefixime
Organisms: Neisseria gonorrhoeae
Papers: 1

Paper Information1

1

Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.

PMID 19528266 · 2009

Mutation Information

Protein Change: G45D
Organisms: Neisseria gonorrhoeae
Confers Resistance To: ceftriaxone|cefixime

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

disrupts the DNA-binding domain of the MtrR repressor

Source Database

Reslit

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research