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© 2026 ResLit. Data sourced from PubMed literature analysis.

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Browse Mutations macAG353A

GenemacA

Nucleotide ChangeG353A

Validation StatusCandidate

Databases

Reslit

Overview

Mechanism: reduces resistance to macrolides in vivo
Resistance To: Macrolide
Organisms: Escherichia coli
Papers: 1

Paper Information1

1

The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter.

PMID 21696464 · 2011

The G353A mutation in MacA reduces resistance to macrolides in vivo.

Mutation Information

Nucleotide Change: G353A
Organisms: Escherichia coli
Confers Resistance To: Macrolide

ResLit

A curated database of antimicrobial resistance genes and mutations extracted from scientific literature.

Browse

AMR Genes
AMR Mutations

Resources

About ResLit
Collaborators
PubMed
NCBI Pathogens
UniProt
CARD
ResFinder DB
PointFinder DB
AMR Rules

Curators

Curator Login
Dashboard

Effect on Function

reduces resistance to macrolides in vivo

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© 2026 ResLit. Data sourced from PubMed literature analysis.

Built for antimicrobial resistance research