ResLit - Antimicrobial Resistance Gene & Mutation Database

Protein ChangeN538I

Validation StatusCandidate

Databases

Reslit

Overview

Resistance To: Fluoroquinolones
Organisms: Mycobacterium tuberculosis
Papers: 1

Paper Information1

High proportion of fluoroquinolone-resistant Mycobacterium tuberculosis isolates with novel gyrase polymorphisms and a gyrA region associated with fluoroquinolone susceptibility.

PMID 22189117 · 2012

This mutation was identified in a fluoroquinolone-resistant isolate and is associated with reduced susceptibility to fluoroquinolones.

Mutation Information

gyrB: p.N538I

Protein Change: N538I
Organisms: Mycobacterium tuberculosis
Confers Resistance To: Fluoroquinolones
Source Database: Reslit

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