GenekatG
Protein ChangeS315N
Validation StatusCandidate
Databases
Reslit
Overview
- Resistance To
- isoniazid
- Organisms
- Mycobacterium tuberculosis
- Papers
- 2
Paper Information2
1
Rapid direct detection of multiple rifampin and isoniazid resistance mutations in Mycobacterium tuberculosis in respiratory samples by real-time PCR.
Mutation Information
- Protein Change
- S315N
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- isoniazid
- Source Database
- Reslit
2
Isoniazid-resistance conferring mutations in Mycobacterium tuberculosis KatG: catalase, peroxidase, and INH-NADH adduct formation activities.
Mutations in KatG are associated with isoniazid resistance through reduced INH-NADH adduct formation.
Mutation Information
- Protein Change
- S315N
- Organisms
- Mycobacterium tuberculosis
- Confers Resistance To
- isoniazid
- Source Database
- Reslit
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