Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Overview
Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump.
Mutation in gyrA contributes to fluoroquinolone resistance
Comparative in vitro activities of ciprofloxacin, clinafloxacin, gatifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against Klebsiella pneumoniae, Klebsiella oxytoca, Enterobacter cloacae, and Enterobacter aerogenes clinical isolates with alterations in GyrA and ParC proteins.
mutations in gyrA are associated with fluoroquinolone resistance
gyrA
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from pigs to humans, Taiwan.
Development and validation of a diagnostic DNA microarray to detect quinolone-resistant Escherichia coli among clinical isolates.
Single nucleotide exchange at position 83
Characterization of isolates of Salmonella enterica serovar typhimurium displaying high-level fluoroquinolone resistance in Japan.
Contribution of target gene mutations and efflux to decreased susceptibility of Salmonella enterica serovar typhimurium to fluoroquinolones and other antimicrobials.
Analysis of ciprofloxacin-resistant Salmonella strains from swine, chicken, and their carcasses in Taiwan and detection of parC resistance mutations by a mismatch amplification mutation assay PCR.
The clinical and microbiological characteristics of enteric fever in Cambodia, 2008-2015.
Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients.
A Multifactorial Approach for Surveillance of Shigella spp. and Entero-Invasive Escherichia coli Is Important for Detecting (Inter)national Clusters.
Phylogenomic Investigation of Increasing Fluoroquinolone Resistance among Belgian Cases of Shigellosis between 2013 and 2018 Indicates Both Travel-Related Imports and Domestic Circulation.
Mutations in gyrA are associated with ciprofloxacin resistance.
A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at pathogenwatch.
Shared and Unique Evolutionary Trajectories to Ciprofloxacin Resistance in Gram-Negative Bacterial Pathogens.
Mutations in gyrA are responsible for ciprofloxacin resistance in E. coli, A. baumannii, and P. aeruginosa.
Distribution of fluoroquinolone resistance determinants in Carbapenem-resistant Klebsiella pneumoniae clinical isolates associated with bloodstream infections in China.
Antimicrobial resistance and genomic characterization of Salmonella Dublin isolates in cattle from the United States.
Genomic epidemiology of persistently circulating MDR Shigella sonnei strains associated with men who have sex with men (MSM) in Belgium (2013-19).
Transmission Dynamics of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 Strains Carrying Capsular Loci KL64 and rmpA/rmpA2 Genes.
The Evolution of Fluoroquinolone Resistance in Salmonella under Exposure to Sub-Inhibitory Concentration of Enrofloxacin.
mutations in QRDR region
Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars.
Common mutation in S. Typhi and other Salmonella serovars.
Mutations in gyrA are common in quinolone-resistant Salmonella isolates.
Diversity in the Characteristics of Klebsiella pneumoniae ST101 of Human, Environmental, and Animal Origin.
Genome and antibiotic resistance characteristics of Shigella clinical isolates in Fujian Province, Southeast China, 2005-2019.
Mutations in gyrA and parC contribute to quinolone resistance.
Unveiling the Genetic Diversity and Antimicrobial Resistance Profiles of Salmonella Population From 2016 to 2020 in Thai Canal Water.
Double amino acid substitutions in both positions of GyrA (S83F, D87N) and ParC (T57S, S80I) were observed in only S. Kentucky ST198 strains.
Detection of Decreased Fluoroquinolone Susceptibility in Salmonellas and Validation of Nalidixic Acid Screening Test
Molecular epidemiology of extended-spectrum beta-lactamase-producing, fluoroquinolone-resistant isolates of Klebsiella pneumoniae in Taiwan.
Mutations in gyrA were associated with quinolone resistance in K. pneumoniae isolates.
Use of a LightCycler gyrA mutation assay for rapid identification of mutations conferring decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates.
Mutations in gyrA confer decreased susceptibility to ciprofloxacin in multiresistant Salmonella enterica serotype Typhimurium DT104 isolates.
Ciprofloxacin-resistant Salmonella Kentucky in travelers.
Mutations in gyrA lead to ciprofloxacin resistance.
Molecular analysis of fluoroquinolone-resistant Salmonella Paratyphi A isolate, India.
Positive epistasis drives the acquisition of multidrug resistance.
Prevalence, resistance mechanisms, and susceptibility of multidrug-resistant bloodstream isolates of Pseudomonas aeruginosa.
Multidrug-Resistant Shigella Infections in Patients with Diarrhea, Cambodia, 2014-2015.
Common mutation in gyrA at position 83
Molecular Epidemiology and Clinical Characterization of Carbapenemase-Producing Enterobacter Species From an International Cohort.
Antimicrobial Resistance of Salmonella enterica Serovar Typhimurium in Shanghai, China.
Mutations in gyrA and parC genes contribute to ciprofloxacin resistance.
Prevalence of plasmid-mediated quinolone resistance in Escherichia coli isolated from diseased animals in Taiwan.
Genomic epidemiology of emerging ESBL-producing Salmonella Kentucky bla (CTX-M-14b) in Europe.
Genomic Serotyping, Clinical Manifestations, and Antimicrobial Resistance of Nontyphoidal Salmonella Gastroenteritis in Hospitalized Children in Ho Chi Minh City, Vietnam.
associated with ciprofloxacin resistance
Regional Variation of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacterales, Fluoroquinolone-Resistant Salmonella enterica and Methicillin-Resistant Staphylococcus aureus Among Febrile Patients in Sub-Saharan Africa.
Mutations observed in Salmonella enterica isolates from Burkina Faso and Tanzania.
Mechanisms for Development of Ciprofloxacin Resistance in a Clinical Isolate of Pseudomonas aeruginosa.
Comparative genomic and phenotypic characterization of invasive non-typhoidal Salmonella isolates from Siaya, Kenya.
Two substitutions, D87G and D94G, found in the chromosomal DNA gyrase protein GyrA
The genomic epidemiology of multi-drug resistant invasive non-typhoidal Salmonella in selected sub-Saharan African countries.
Mutations in gyrA confer resistance to fluoroquinolones.
Acquisition and loss of CTX-M plasmids in Shigella species associated with MSM transmission in the UK.
Single mutation in 2018 S. sonnei strains, triple mutations in 2020 S. sonnei strain
Genomic Epidemiology of Multidrug-Resistant Nontyphoidal Salmonella in Young Children Hospitalized for Gastroenteritis.
Multiple Novel Traits without Immediate Benefits Originate in Bacteria Evolving on Single Antibiotics.
Mutations in gyrA confer resistance to quinolone antibiotics.
Genetic and in-silico approaches for investigating the mechanisms of ciprofloxacin resistance in Salmonella typhi: Mutations, extrusion, and antimicrobial resistance.
Nonlinear impacts of temperature on antibiotic resistance in Escherichia coli.
Retrospective analysis of antimicrobial resistance associated with bovine respiratory disease.
Stool carriage of CTX-M/CMY-producing Salmonella enterica in a Chinese tertiary hospital in Shenzhen, China.
Dogs fed raw meat-based diets are vectors of drug-resistant Salmonella infection in humans.
Mutation in quinolone resistance-determining region
Single-nucleotide polymorphism mutation spectra and resistance to quinolones in Salmonella enterica serovar Enteritidis with a mutator phenotype.
Mutations in the quinolone resistance-determining region (QRDR) of gyrA were associated with resistance to quinolones.
Role of electronic data exchange in an international outbreak caused by Salmonella enterica serotype Typhimurium DT204b.
Decreased susceptibility to ciprofloxacin
Ciprofloxacin-resistant Salmonella enterica serovar Typhimurium strains are difficult to select in the absence of AcrB and TolC.
Characterisation of Salmonella Enteritidis ST11 and ST1925 Associated with Human Intestinal and Extra-Intestinal Infections in Singapore.
Introduction and establishment of fluoroquinolone-resistant Shigella sonnei into Bhutan.
Time-Resolved Tracking of Mutations Reveals Diverse Allele Dynamics during Escherichia coli Antimicrobial Adaptive Evolution to Single Drugs and Drug Pairs.
Phylogenetic and Evolutionary Analysis Reveals the Recent Dominance of Ciprofloxacin-Resistant Shigella sonnei and Local Persistence of S. flexneri Clones in India.
Mutations in gyr A contribute to fluoroquinolone resistance.
The role of chemotaxis and efflux pumps on nitrate reduction in the toxic regions of a ciprofloxacin concentration gradient.
Clinical and molecular characteristics of Chryseobacterium indologenes isolates at a teaching hospital in Shanghai, China.
Mutations in GyrA contribute to quinolone resistance.
Bactericidal activities and post-antibiotic effects of ofloxacin and ceftriaxone against drug-resistant Salmonella enterica serovar Typhi.
Single point mutation in the QRDR of the gyrA gene
Molecular Characterization of Cephalosporin and Fluoroquinolone Resistant Salmonella Choleraesuis Isolated from Patients with Systemic Salmonellosis in Thailand.
Emergence of mcr-1-Harboring Salmonella enterica Serovar Sinstorf Type ST155 Isolated From Patients With Diarrhea in Jiangsu, China.
Mutations in gyrA contribute to ciprofloxacin resistance.
Extensive Drug-Resistant Salmonella enterica Isolated From Poultry and Humans: Prevalence and Molecular Determinants Behind the Co-resistance to Ciprofloxacin and Tigecycline.
Mutations in gyrA gene were detected at codon S83 or D87 or both in 89.66% of XDR Salmonella.
Global population structure of the Serratia marcescens complex and identification of hospital-adapted lineages in the complex.
Research note: The resistome of commensal Escherichia coli isolated from broiler carcasses "produced without the use of antibiotics"(a).
Increased Severity of Multidrug-Resistant Shigella sonnei Infections in People Experiencing Homelessness.
Prevalence and characterization of ciprofloxacin-resistant Salmonella enterica spp. isolated from food animals during 2010-2023 in South Korea.
Genomic and epidemiological characteristics of Shigella boydii in Australia, 1991-2022.
Genomic analyses reveal presence of extensively drug-resistant Salmonella enterica serovars isolated from clinical samples in Guizhou province, China, 2019-2023.
Mutations in quinolone resistance-determining regions (QRDRs)
Exploring the potential role of GyrA inhibiting quinoline analog: an in silico study.
All mutations are in the quinolone resistance-determining region (QRDR) of gyrA.
The effect of commonly used non-antibiotic medications on antimicrobial resistance development in Escherichia coli.
Mutations in GyrA are associated with fluoroquinolone resistance, leading to reduced susceptibility to ciprofloxacin.
Mutations in gyrA, such as S83L and D87G, reduce susceptibility to fluoroquinolones, contributing to ciprofloxacin resistance.
Analyzing Shigella in Wuhan: Serotypes, Antimicrobial Resistance, and Public Health Implications.
Genomic evolution of Salmonella Dublin in cattle and humans in the United States.
Lytic phages obscure the cost of antibiotic resistance in Escherichia coli.
Structure based in silico analysis of quinolone resistance in clinical isolates of Salmonella Typhi from India.
Mutations in the QRDR of gyrA are responsible for quinolone resistance in S. Typhi.
Mutations in DNA Gyrase alter the characteristics of the binding pocket resulting in the loss of crucial molecular interactions and consequently decrease the binding affinity of fluoroquinolones with the target protein.
Phenotypic and genetic characterization of antimicrobial resistance in Salmonella enterica serovar Choleraesuis isolates from humans and animals in Spain from 2006 to 2021.
Emergence and Diversity of Salmonella enterica Serovar Indiana Isolates with Concurrent Resistance to Ciprofloxacin and Cefotaxime from Patients and Food-Producing Animals in China.
S. Enteritidis and S. Typhimurium Harboring SPI-1 and SPI-2 Are the Predominant Serotypes Associated With Human Salmonellosis in Saudi Arabia.
Comparative Genomics and Phenotypic Investigations Into Antibiotic, Heavy Metal, and Disinfectant Susceptibilities of Salmonella enterica Strains Isolated in Australia.
Mutation in gyrA leads to resistance to nalidixic acid
Molecular Epidemiology of Multidrug-Resistant Klebsiella pneumoniae Isolates in a Brazilian Tertiary Hospital.
Genomic Features of High-Priority Salmonella enterica Serovars Circulating in the Food Production Chain, Brazil, 2000-2016.
Analysis of isolates from Bangladesh highlights multiple ways to carry resistance genes in Salmonella Typhi.
Mutations in gyrA are associated with ciprofloxacin resistance.
Informal genomic surveillance of regional distribution of Salmonella Typhi genotypes and antimicrobial resistance via returning travellers.
Mutations in the quinolone resistance determining region (QRDR) of gyrA and parC are associated with reduced susceptibility to fluoroquinolones.
An Outbreak of Carbapenem-Resistant and Hypervirulent Klebsiella pneumoniae in an Intensive Care Unit of a Major Teaching Hospital in Wenzhou, China.
Chromosomal and plasmid-mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana.
Diversity of Serotype, Genotype, and Antibiotic Susceptibility of Salmonella Prevalent in Pickled Ready-to-Eat Meat.
Mutations in GyrA contribute to quinolone resistance.
Ciprofloxacin-Resistant Salmonella enterica Serovar Kentucky ST198 in Broiler Chicken Supply Chain and Patients, China, 2010-2016.
Mutations in gyrA contribute to nalidixic acid resistance.
Pathogenomics and Evolutionary Epidemiology of Multi-Drug Resistant Clinical Klebsiella pneumoniae Isolated from Pretoria, South Africa.
Genomic analysis of Salmonella isolated from canal water in Bangkok, Thailand.
Predominance of multidrug-resistant Salmonella Typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar.
Type II Topoisomerase Mutations in Ciprofloxacin-Resistant Strains of Pseudomonas aeruginosa.
Most common mutation
Multiplex Real-Time Polymerase Chain Reaction-Based Method for the Rapid Detection of gyrA and parC Mutations in Quinolone-Resistant Escherichia coli and Shigella spp.
Fitness benefits in fluoroquinolone-resistant Salmonella Typhi in the absence of antimicrobial pressure.
Lack of efflux mediated quinolone resistance in Salmonella enterica serovars Typhi and Paratyphi A.
associated with resistance
Molecular characterization and PCR-based replicon typing of multidrug resistant Shigella sonnei isolates from an outbreak in Thimphu, Bhutan.
Fluoroquinolone resistance in Salmonella: insights by whole-genome sequencing.
chromosomal mutations in gyrA contribute to fluoroquinolone resistance
Salmonella enterica Serovar Typhi in Bangladesh: Exploration of Genomic Diversity and Antimicrobial Resistance.
Mutations in gyrA are associated with ciprofloxacin resistance.
Quinolone resistance phenotype and genetic characterization of Salmonella enterica serovar Pullorum isolates in China, during 2011 to 2016.
The Asp87Gly substitution in GyrA was found in three strains (3/30, 10%).
Mechanisms of reduced susceptibility to ciprofloxacin in Escherichia coli isolates from Canadian hospitals.
Molecular and Physiological Characterization of Fluoroquinolone-Highly Resistant Salmonella Enteritidis Strains.
Mutations in gyrA are associated with fluoroquinolone resistance.
Genomic Investigation of the Emergence of Invasive Multidrug-Resistant Salmonella enterica Serovar Dublin in Humans and Animals in Canada.
Mutations in gyrA lead to fluoroquinolone resistance.
Effects of a previously selected antibiotic resistance on mutations acquired during development of a second resistance in Escherichia coli.
Mutations in gyrA were observed in wild-type E. coli adapted to enrofloxacin.
Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198.
Characterization of Resistance and Virulence of Pasteurella multocida Isolated from Pet Cats in South China.
Mutations in gyrA were associated with fluoroquinolone resistance.
Rapid emergence of extensively drug-resistant Shigella sonnei in France.
Genomic Characterization and Genetic Profiles of Salmonella Gallinarum Strains Isolated from Layers with Fowl Typhoid in Colombia.
A point mutation in recC associated with subclonal replacement of carbapenem-resistant Klebsiella pneumoniae ST11 in China.
mutation associated with fluoroquinolone resistance
Collateral sensitivity: An evolutionary trade-off between antibiotic resistance mechanisms, attractive for dealing with drug-resistance crisis.
Mutation in gyrA (Asp87Gly) leads to resistance to fluoroquinolones and unexpected hypersensitivity to other drugs.
Genomic analysis and antimicrobial activity of β-lactam/β-lactamase inhibitors and other agents against KPC-producing Klebsiella pneumoniae clinical isolates from Brazilian hospitals.
Poultry production as the main reservoir of ciprofloxacin- and tigecycline-resistant extended-spectrum β-lactamase (ESBL)-producing Salmonella enterica serovar Kentucky ST198.2-2 causing human infections in China.
Mutations in gyrA confer resistance to fluoroquinolones.
Phenotypic and genotypic antimicrobial resistance correlation and plasmid characterization in Salmonella spp. isolates from Italy reveal high heterogeneity among serovars.
The Drug-Specific Propensity Regarding the Acquisition of Fluoroquinolone Resistance in Escherichia coli: An in vitro Challenge and DNA Mutation Analysis.
The balance between antibiotic resistance and fitness/virulence in Pseudomonas aeruginosa: an update on basic knowledge and fundamental research.
Mutations in gyrA lead to resistance to quinolones.
Resistance development in Escherichia coli to delafloxacin at pHs 6.0 and 7.3 compared to ciprofloxacin.
Mutations in gyrA were seen in all derivatives challenged with CIP, regardless of pH.
Mutations in the quinolone resistance-determining regions of gyrA and parC in Enterobacteriaceae isolates from Brazil.
Multiple mutations in gyrA and parC genes are associated with high-level fluoroquinolone resistance.
Molecular epidemiology and pathogenomics of extended-spectrum beta-lactamase producing- Escherichia coli and - Klebsiella pneumoniae isolates from bulk tank milk in Tennessee, USA.
Mutations in gyrA contribute to fluoroquinolone resistance.
Distribution of Extended-Spectrum-β-Lactamase-Producing Diarrheagenic Escherichia coli Clonal Complex 10 Isolates from Patients with Diarrhea in the Republic of Korea.
Out of Asia: the independent rise and global spread of fluoroquinolone-resistant Shigella.
mutations in QRDR region of gyrA and parC are primarily responsible for fluoroquinolone resistance in Shigella
Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal: Antimicrobial resistance and implications for vaccine policy.
Mutations in the QRDR of gyrA contribute to fluoroquinolone resistance.
Population structure and antimicrobial resistance patterns of Salmonella Typhi isolates in urban Dhaka, Bangladesh from 2004 to 2016.
Isolation of Drug-Resistant Gallibacterium anatis from Calves with Unresponsive Bronchopneumonia, Belgium.
Molecular epidemiology of Salmonella Infantis in Europe: insights into the success of the bacterial host and its parasitic pESI-like megaplasmid.
Antimicrobial resistance and novel mutations detected in the gyrA and parC genes of Pseudomonas aeruginosa strains isolated from companion dogs.
Mutations in gyrA were significantly more common in strains from the infected group than in those from the healthy group
Genomic profiling of antimicrobial resistance genes in clinical isolates of Salmonella Typhi from patients infected with Typhoid fever in India.
Antimicrobial Resistance in Salmonella enterica Serovar Paratyphi B Variant Java in Poultry from Europe and Latin America.
Phenotypic and Genotypic Properties of Vibrio cholerae non-O1, non-O139 Isolates Recovered from Domestic Ducks in Germany.
Mutation in gyrA gene leads to resistance to nalidixic acid
The prevalence and mechanism of fluoroquinolone resistance in Escherichia coli isolated from swine farms in China.
Mutations in the QRDR region
Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa.
mutations in gyrA contribute to fluoroquinolone resistance in P. aeruginosa
Mutational background influences P. aeruginosa ciprofloxacin resistance evolution but preserves collateral sensitivity robustness.
Emergence of Resistant Escherichia coli Mutants in Microfluidic On-Chip Antibiotic Gradients.
Mutations in gyrA, leading to fluoroquinolone resistance.
Whole genome sequencing analyses revealed that Salmonella enterica serovar Dublin strains from Brazil belonged to two predominant clades.
mcr-1-Mediated Colistin Resistance and Genomic Characterization of Antimicrobial Resistance in ESBL-Producing Salmonella Infantis Strains from a Broiler Meat Production Chain in Italy.
Spread of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Producing NDM-Type Metallo-β-Lactamase in Myanmar.
Prevalence and whole-genome sequencing analysis of Salmonella reveal its spread along the duck production chain.
Mutations in gyrA contribute to nalidixic acid resistance in Salmonella typhimurium.
Genomic and Evolutionary Analysis of Salmonella enterica Serovar Kentucky Sequence Type 198 Isolated From Livestock In East Africa.
Mutations in gyrA and parC confer resistance to ciprofloxacin.
Dynamics of Antimicrobial Resistance and Genomic Epidemiology of Multidrug-Resistant Salmonella enterica Serovar Indiana ST17 from 2006 to 2017 in China.
Mutations in gyrA contribute to fluoroquinolone resistance.
Genomic surveillance of Salmonella spp. in the Philippines during 2013-2014.
Single-cell genomics reveals population structures from in vitro evolutionary studies of Salmonella.
A multicenter genomic epidemiological investigation in Brazil, Chile, and Mexico reveals the diversity and persistence of Salmonella populations in surface waters.
Comparative genomics of quinolone-resistant Escherichia coli from broilers and humans in Norway.
Investigation of gyrA and parC mutations and the prevalence of plasmid-mediated quinolone resistance genes in Klebsiella pneumoniae clinical isolates.
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms.
Mutations in gyrA are associated with resistance to fluoroquinolones.
gyrA mutations associated with fluoroquinolone resistance in eight species of Enterobacteriaceae.
gyrA
Genetic evidence for a role of parC mutations in development of high-level fluoroquinolone resistance in Escherichia coli.
gyrA
Analysis of the mutations involved in fluoroquinolone resistance of in vivo and in vitro mutants of Escherichia coli.
gyrA
Quinolone-resistant gyrase mutants demonstrate decreased susceptibility to triclosan.
gyrA
Escherichia coli gyrA with mutation conferring resistance to triclosan; CARD accession: CARD:3004335
Salmonella enterica gyrA with mutation conferring resistance to triclosan; CARD accession: CARD:3004334
Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals.
gyrA
Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.
gyrA
DNA gyrase gyrA mutations in quinolone-resistant clinical isolates of Pseudomonas aeruginosa.
gyrA
Pseudomonas aeruginosa gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003684
Mechanisms of quinolone resistance in Escherichia coli and Salmonella: recent developments.
gyrA
Characterisation of novel mutations involved in quinolone resistance in Escherichia coli isolated from imported shrimp.
Escherichia coli gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3003294
Antibiotic resistance of Helicobacter pylori in Nanjing, China: a cross-section study from 2018 to 2023.
Helicobacter pylori gyrA conferring resistance to fluoroquinolones; CARD accession: CARD:3007052
Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals.
D87G or D87Y confer resistance to nalidixic acid only, if occurring alone. Unknown phenotype if D87H occurs alone
4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction.
D87G or D87Y confer resistance to nalidixic acid only, if occurring alone. Unknown phenotype if D87H occurs alone
Detection of mutations in the gyrA and parC genes in Escherichia coli isolates carrying plasmid-mediated quinolone resistance genes from diseased food-producing animals.
D87G or D87Y confer resistance to nalidixic acid only, if occurring alone. Unknown phenotype if D87H occurs alone
High prevalence of acquired quinolone-resistance genes among Enterobacteriaceae from Saudi Arabia with CTX-M-15 β-lactamase.
Under development. Phenotype should be used with caution.
Salmonella typhimurium gyrA mutations associated with fluoroquinolone resistance.
Comparative studies of mutations in animal isolates and experimental in vitro- and in vivo-selected mutants of Salmonella spp. suggest a counterselection of highly fluoroquinolone-resistant strains in the field.
[Resistance to quinolones and beta-lactams in Salmonella enterica due to mutations in topoisomerase-encoding genes, altered cell permeability and expression of an active efflux system].
Quinolone resistance among Escherichia coli strains from community-acquired urinary tract infections in Greece.
Most frequent mutation
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