Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| V131fs | - | frameshift mutation | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | V139A | loss of PZAse activity, single resistance variant | Mycobacterium tuberculosis | pyrazinamidepza | Card DatabaseReslit | Confirmed | |
| V139E | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | V139G | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed | |
pncA pyrazinamidase | V139L | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed | |
pncA pyrazinamidase | V139M | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
| V147A | - | single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card Database | Established | |
pncA pyrazinamidase | V147I | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | V154A | - | - | Mycobacterium tuberculosis | pyrazinamide | Reslit | Candidate |
pncA pyrazinamidase | V155A | - | loss of PZAse activity, single resistance variant | Mycobacterium tuberculosis | pyrazinamide | Card DatabaseReslit | Confirmed |
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