Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
porB outer membrane porin | G120K | decreased permeability of the cell membrane, decreased membrane permeability, reducing membrane permeability for hydrophilic antibiotics | Neisseria gonorrhoeae, Neisseria subflava | penicillinceftriaxonetetracycline+2 more | ResFinder DatabaseReslit | Confirmed | |
| G120P | - | - | Neisseria gonorrhoeae | penicillintetracyclinecephalosporins | ResFinder Database | Established | |
| G120R | - | - | Neisseria gonorrhoeae | penicillintetracyclinecephalosporins | ResFinder Database | Established | |
porB outer membrane porin PorB | G120X | - | - | Neisseria gonorrhoeae | ceftriaxone | Reslit | Candidate |
porB trimeric porin PorB.IB | G140K | - | - | - | ceftriaxone | Reslit | Candidate |
| L421P | - | - | Neisseria gonorrhoeae | ceftriaxone | Reslit | Candidate | |
porB porin | N122K | - | - | Neisseria gonorrhoeae | penicillinceftriaxone | Reslit | Candidate |
porB trimeric porin PorB.IB | N134E | - | - | - | ceftriaxone | Reslit | Candidate |
porB trimeric porin PorB.IB | Q143E | - | - | - | ceftriaxone | Reslit | Candidate |
porB trimeric porin PorB.IB | Q143G | - | - | - | ceftriaxone | Reslit | Candidate |
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