Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	A477D	G1430A GCC->GAT	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicinvancomycindaptomycin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB	A477G	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene Catalog	Established
rpoB β-subunit of RNA polymerase	A477S	-	-	-	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta-subunit	A477T	-	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	A477V	-	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicinbeta lactams	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	A478D	G1432A	-	Bacillus subtilis	rifampicin	Reslit	Candidate
rpoB	A478N	-	single resistance variant	Bacillus subtilis	rifampicin	Card Database	Established
rpoB β subunit of RNA polymerase	A532S	-	-	Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	A532V	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	A621E	-	The rpoB(A621E) mutation conferred N315ΔIP with the phenotypes of reduced susceptibility to daptomycin and hetero-VISA., single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	daptomycinvancomycin	Card DatabaseReference Gene CatalogReslit	Confirmed