Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	H485C	-	The H485C mutation in rpoB confers rifampicin resistance in B. velezensis.	Bacillus velezensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H485D	-	The H485D mutation in rpoB confers rifampicin resistance in B. velezensis.	Bacillus velezensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H485R	-	The H485R mutation in rpoB confers rifampicin resistance in B. velezensis.	Bacillus velezensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H485Y	-	The H485Y mutation in rpoB confers rifampicin resistance in B. velezensis.	Bacillus velezensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H486N	-	-	Streptococcus mitis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H486Y	-	upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic, DNA-directed RNA polymerase subunit beta RpoB	Enterococcus faecium	rifampicindaptomycinrifaximin	Reference Gene CatalogReslit	Confirmed
rpoB RNA polymerase beta subunit	H487D	-	-	Lactobacillus rhamnosus	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H490Y	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H491D	-	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	H491N	C1472T	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate