Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	L533E	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L533P	CTG-CCG CTT->CCT T1600C	did not significantly change the intermolecular interaction between RpoB and RIF, Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Mycobacterium tuberculosis, Mycobacterium smegmatis, Escherichia coli, Shigella sonnei	rifampicinrifabutinrifamycins	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	L533Q	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L533R	CTT->CGT	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase β-chain	L538I	-	-	Pseudomonas aeruginosa	rifampicin	Reslit	Candidate
rpoB β-subunit of RNA polymerase	L538P	-	-	Pseudomonas fluorescens	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	L547F	-	-	Helicobacter pylori	rifampicin	Reslit	Candidate
rpoB	L560S	-	DNA-directed RNA polymerase subunit beta RpoB	Neisseria gonorrhoeae	rifampicin	Reference Gene Catalog	Established
rpoB RNA polymerase beta subunit	L571Q	-	-	-	rifampicin	Reslit	Candidate
rpoB	L584F	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	rifaximin	Reference Gene Catalog	Established