Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase β-chain	N629S	-	-	Pseudomonas aeruginosa	rifampicin	Reslit	Candidate
rpoB RNA polymerase β subunit	N967I	-	confers high-dose methicillin tolerance and promotes heterogeneous-to-homogeneous conversion of β-lactam resistance, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	methicillinbeta lactams	Reference Gene CatalogReslit	Confirmed
rpoB	P157L	-	DNA-directed RNA polymerase subunit beta RpoB	Neisseria gonorrhoeae	cephalosporins	Reference Gene Catalog	Established
rpoB RNA polymerase beta subunit	P177S	C531T	-	Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	P206T	-	-	Mycobacterium tuberculosis	rifampicinrifabutin	Reslit	Candidate
rpoB RNA polymerase beta subunit	P230L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	P280L	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB beta-subunit of the DNA-dependent RNA polymerase	P353L	C1057T	-	Listeria monocytogenes	rifampicin	Reslit	Candidate
rpoB	P439A	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	P439L	C1318T	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseReslit	Confirmed