Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	Q468R	C1403G	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q469K	-	single resistance variant	Staphylococcus epidermidis, Bacillus subtilis	rifampicin	Card DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q469L	-	-	Staphylococcus epidermidis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q469R	-	single resistance variant	Staphylococcus epidermidis, Bacillus subtilis	rifampicincefotaxime	Card DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q472R	-	The Q472R mutation in rpoB confers rifampicin resistance in B. velezensis.	Bacillus velezensis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q473K	-	-	Enterococcus faecium	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q473L	-	upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic	Enterococcus faecium	daptomycin	Reslit	Candidate
rpoB DNA-directed RNA polymerase beta chain	Q474R	-	-	Flavobacterium psychrophilum	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	Q486L	-	-	Streptococcus pneumoniae, Staphylococcus aureus	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q486R	-	-	Staphylococcus aureus	rifampicin	Reslit	Candidate