Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	Q513K	CAA->AAA	-	Mycobacterium tuberculosis	rifampicin	Reslit	Supported
rpoB RNA polymerase beta subunit	Q513L	A1538T A1540T	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Escherichia coli, Mycobacterium tuberculosis, Shigella sonnei	rifampicinrifabutinrifapentine+1 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB β subunit of RNA polymerase	Q513N	-	-	Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q513P	CAA->CCC	Target modification, single resistance variant, DNA-directed RNA polymerase subunit beta RpoB	Escherichia coli, Mycobacterium tuberculosis, Shigella sonnei	rifampicinrifabutinrifapentine+1 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	Q513Q	CAA->CAA	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q513R	A1540G	-	Mycobacterium tuberculosis, Escherichia coli	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	Q513V	-	-	Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB β subunit of RNA polymerase	Q517H	-	-	Mycobacterium smegmatis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	Q517Q	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB	Q517QDQ	-	DNA-directed RNA polymerase subunit beta RpoB	Shigella sonnei	rifampicin	Reference Gene Catalog	Established