Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	R483H	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R484C	-	DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogReslit	Confirmed
rpoB RNA polymerase beta subunit	R484H	-	Target modification, DNA-directed RNA polymerase subunit beta RpoB	Staphylococcus aureus	rifampicin	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	R484S	-	-	Staphylococcus aureus	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R485H	-	-	Staphylococcus epidermidis	rifampicin	Reslit	Candidate
rpoB DNA-directed RNA polymerase subunit beta	R489H	-	-	Enterococcus faecalis	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R494K	-	-	Riemerella anatipestifer	rifampicin	Reslit	Candidate
rpoB RNA polymerase beta subunit	R503H	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
rpoB β subunit of RNA polymerase	R505K	G1514A CGT->AAA C1514A	single resistance variant, multiple resistance variants, DNA-directed RNA polymerase subunit beta RpoB	Clostridium difficile, Mycobacterium tuberculosis, Clostridioides difficile, Clostridium ljungdahlii	rifampicinrifaximinrifamycins	Card DatabaseReference Gene CatalogReslit	Confirmed
rpoB	R505L	-	DNA-directed RNA polymerase subunit beta RpoB	Clostridioides difficile	rifaximin	Reference Gene Catalog	Established