Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
rpoB RNA polymerase beta subunit	S441A	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseReslit	Confirmed
rpoB	S441K	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	S441L	AGC->CTC	single resistance variant, multiple resistance variants	Mycobacterium tuberculosis, Mycobacterium smegmatis, Mycobacterium bovis	capreomycinrifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB	S441M	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	S441Q	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase beta subunit	S441S	-	-	Mycobacterium tuberculosis	rifampicin	Reslit	Candidate
rpoB	S441V	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB	S441Var	-	single resistance variant	Mycobacterium tuberculosis	rifampicin	Card Database	Established
rpoB RNA polymerase beta subunit	S441W	AGC->TGG	single resistance variant	Mycobacterium tuberculosis, Mycobacterium smegmatis	capreomycinrifampicin	Card DatabaseResFinder DatabaseReslit	Confirmed
rpoB RNA polymerase β subunit	S442F	C1325T	DNA-directed RNA polymerase subunit beta RpoB	Streptomyces albus, Corynebacterium diphtheriae	rifampicinrifamycins	Reference Gene CatalogReslit	Confirmed