Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
rpoB RNA polymerase subunit | S492L | - | - | Escherichia coli | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | S493L | - | single resistance variant | Mycobacterium tuberculosis | rifampicin | Card DatabaseResFinder DatabaseReslit | Confirmed |
rpoB RNA polymerase beta subunit | S493R | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate | |
| S498T | - | single resistance variant | Clostridium ljungdahlii | rifampicin | Card Database | Established | |
rpoB β-subunit of RNA polymerase | S499F | - | - | Salmonella enterica | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | S507L | - | DNA-directed RNA polymerase subunit beta RpoB | Mycobacterium tuberculosis, Clostridioides difficile | rifampicinrifaximin | Reference Gene CatalogReslit | Confirmed |
rpoB RNA polymerase beta subunit | S508L | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | S509P | - | - | Rhodococcus equi | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | S509R | - | - | Mycobacterium tuberculosis | rifampicin | Reslit | Candidate |
rpoB RNA polymerase beta subunit | S512F | - | Escherichia coli, Mycobacterium smegmatis, Salmonella enterica | rifampicin | Reslit | Supported |
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