Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Card Database |
| Established |
| S441W | single resistance variant | Mycobacterium tuberculosis, Mycobacterium smegmatis | CAPRifampicin | Card DatabaseResFinder DatabaseReslit | Confirmed |
| S442F | DNA-directed RNA polymerase subunit beta RpoB | Streptomyces albus, Corynebacterium diphtheriae | RifampinRIFAMYCIN | Reference Gene CatalogReslit | Confirmed |
| S442N | - | DNA-directed RNA polymerase subunit beta RpoB | Corynebacterium diphtheriae | RIFAMYCIN | Reference Gene Catalog | Established |
| S442Y | The mutation causes a serine to tyrosine substitution at position 442, leading to a more hydrophobic environment in the rifampin binding pocket, which reduces the effectiveness of rifampin., DNA-directed RNA polymerase subunit beta RpoB | Streptomyces albus, Corynebacterium diphtheriae | RifampinRIFAMYCIN | Reference Gene CatalogReslit | Confirmed |
| S443F | - | - | Rhodococcus equi | Rifampin | Reslit | Candidate |
| S444F | - | Corynebacterium diphtheriae, Corynebacterium urealyticum | Rifampicin | Reslit | Candidate |
| S444N | - | - | Corynebacterium urealyticum | Rifampicin | Reslit | Candidate |
| S445L | - | - | Mycobacterium tuberculosis | Rifampicin | Reslit | Candidate |
© 2026 ResLit. Data sourced from PubMed literature analysis.
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