Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| S490L | - | The S490L mutation in rpoB confers rifampicin resistance in B. velezensis. | Bacillus velezensis | Rifampicin | Reslit | Candidate | |
| S491F | - | upregulation of a previously uncharacterized operon (prdRAB) that leads to cell membrane remodelling and cross-resistance to daptomycin through reduced binding of the antibiotic, mutated |
| Enterococcus faecium |
DaptomycinDaptomycin|Rifampicin |
Reslit |
| Candidate |
| S491L | - | - | Enterococcus faecium | Rifampin | Reslit | Candidate |
| S492F | - | - | Flavobacterium psychrophilum | Rifampicin | Reslit | Candidate |
| S492L | - | - | Escherichia coli | Rifampin | Reslit | Candidate |
| S493L | - | single resistance variant | Mycobacterium tuberculosis | Rifampicin | Card DatabaseResFinder DatabaseReslit | Confirmed |
| S493R | - | Mycobacterium tuberculosis | Rifampicin | Reslit | Candidate |
| S498T | - | single resistance variant | Clostridium ljungdahlii | Rifampicin | Card Database | Established |
| S499F | - | - | Salmonella enterica | Rifampicin | Reslit | Candidate |
| S507L | - | DNA-directed RNA polymerase subunit beta RpoB | Mycobacterium tuberculosis, Clostridioides difficile | RifampicinRIFAXIMIN | Reference Gene CatalogReslit | Confirmed |
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