Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
blaL1a metallo-beta-lactamase | H151V | - | - | Escherichia coli | ceftazidimecefepimeimipenem+2 more | Reslit | Candidate |
blaL1a metallo-beta-lactamase | P225A | - | - | Escherichia coli | ceftazidimecefepimeimipenem+2 more | Reslit | Candidate |
blaL1a metallo-beta-lactamase | R236A | - | - | Escherichia coli | ceftazidimecefepimeimipenem+2 more | Reslit | Candidate |
blaL1a metallo-beta-lactamase | Y227A | - | - | Escherichia coli | ceftazidimecefepimeimipenem+2 more | Reslit | Candidate |
blaL2 beta-lactamase | F72I | - | reduced resistance | Escherichia coli, Stenotrophomonas maltophilia | ceftazidimecephalexinaztreonam+6 more | Reslit | Candidate |
blaL2 beta-lactamase | I72F | - | enhanced resistance | Escherichia coli, Stenotrophomonas maltophilia | ceftazidimecephalexinaztreonam+6 more | Reslit | Candidate |
blaLRA-5 β-lactamase | V166E | - | - | E. coli | cephalosporinspenicillinampicillin+4 more | Reslit | Candidate |
blaLRA-5 β-lactamase | Y69Q | - | - | E. coli | cephalosporinspenicillinampicillin+4 more | Reslit | Candidate |
blaNDM-1 metallobeta-lactamase | - | reduced catalytic efficiency and stability | Escherichia coli, Enterobacter cloacae | ampicillincefotaximeceftazidime+3 more | Reslit | Candidate | |
blaNDM-1 metallo-beta-lactamase | D124A | - | - | E. coli, Klebsiella pneumoniae | carbapenems | Reslit | Candidate |
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