Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| - |
| single resistance variant |
| Mycobacterium tuberculosis |
Para-aminosalicylic acidPara-aminosalicyclic acid |
Card DatabaseResFinder DatabaseReslit |
| Confirmed |
| L143P | - | The mutation leads to changes in the dUMP and MTHF binding sites, weak interaction of ThyA enzyme with dUMP and MTHF, loss of hydrogen bond and other atomic interactions, and enhanced movement of protein atoms. | Mycobacterium tuberculosis | Para-aminosalicylic acid | Reslit | Candidate |
| L172P | - | The mutation leads to changes in the dUMP and MTHF binding sites, weak interaction of ThyA enzyme with dUMP and MTHF, loss of hydrogen bond and other atomic interactions, and enhanced movement of protein atoms. | Mycobacterium tuberculosis | Para-aminosalicylic acid | Reslit | Candidate |
| L214Q | - | - | Staphylococcus aureus | Trimethoprim-sulfamethoxazole | Reslit | Candidate |
| L2Q | - | - | Staphylococcus aureus | Trimethoprim-sulfamethoxazole | Reslit | Candidate |
| L2W | - | - | Staphylococcus aureus | Trimethoprim-sulfamethoxazole | Reslit | Candidate |
| N92K | - | - | Staphylococcus aureus | Trimethoprim-sulfamethoxazole | Reslit | Candidate |
| P224L | - | single resistance variant | Mycobacterium tuberculosis | Para-aminosalicyclic acidPara-aminosalicylic acid | Card DatabaseResFinder Database | Confirmed |
| P303G | - | - | Staphylococcus aureus | Trimethoprim-sulfamethoxazole | Reslit | Candidate |
© 2026 ResLit. Data sourced from PubMed literature analysis.
Built for antimicrobial resistance research
Page 1322 of 1368 (13,671 results)