Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ddn deoxyribodipyrimidine photolyase | E35K | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate | |
ddn nitroreductase | G53C | - | - | - | delamanid | Reslit | Candidate |
ddn putative membrane-bound transcriptional activator | G81D | - | - | Mycobacterium tuberculosis | delamanid | Reslit | Candidate |
ddn delamanid-nitroreductase | G81S | - | likely to confer resistance | Mycobacterium tuberculosis | delamanidpretomanid | Reslit | Supported |
ddn F420-dependent nitroreductase | L107P | - | - | - | delamanid | Reslit | Candidate |
| L49P | - | single resistance variant | Mycobacterium tuberculosis | delamanidpretomanidmultiple antibiotics | Card DatabaseReslit | Confirmed | |
ddn deazaflavin-dependent nitroreductase | L64P | - | - | - | pretomanid | Reslit | Candidate |
| M1Var | - | single resistance variant | Mycobacterium tuberculosis | multiple antibiotics | Card Database | Established | |
ddn nitroreductase | P63Q | - | - | - | delamanid | Reslit | Candidate |
ddn deazaflavin-dependent nitroreductase | Q125K | - | - | Mycobacterium smegmatis | pa 824 | Reslit | Candidate |
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