Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
folP dihydropteroate synthase	F17L	TTT->CTT	Primary mutation that is directly associated with sulfonamide resistance, dihydropteroate synthase FolP	Staphylococcus aureus	sulfamethoxazolesulfonamides	Reference Gene CatalogReslit	Confirmed
folP Dihydrofolate synthase	F211L	-	-	Brucella melitensis	sulfamethoxazole	Reslit	Candidate
folP dihydropteroate synthase	F246Y	-	-	Campylobacter jejuni	sulfonamides	Reslit	Candidate
folP	F25I	-	single resistance variant, dihydropteroate synthase FolP	Streptococcus pyogenes	sulfonamides	Card DatabaseReference Gene Catalog	Confirmed
folP dihydropteroate synthase	F28I	-	dihydropteroate synthase FolP	Salmonella Gallinarum, Escherichia coli, Salmonella enterica	sulfonamidessulfamethoxazole	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
folP dihydropteroate synthase	F28L	-	dihydropteroate synthase FolP	Salmonella Gallinarum, Escherichia coli, Salmonella enterica	sulfonamidessulfamethoxazole	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
folP dihydropteroate synthase	F31L	-	dihydropteroate synthase FolP	Neisseria gonorrhoeae, Neisseria meningitidis	sulfonamides	Reference Gene CatalogReslit	Confirmed
folP Dihydropteroate synthase	F4Y	-	-	Escherichia coli	sulfonamides	Reslit	Candidate
folP	G189C	-	dihydropteroate synthase FolP	Haemophilus influenzae	sulfonamides	Reference Gene Catalog	Established
folP dihydropteroate synthase	G194C	-	dihydropteroate synthase FolP	Neisseria gonorrhoeae, Neisseria meningitidis	sulfonamides	Reference Gene CatalogReslit	Confirmed