Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ftsI penicillin-binding protein 3	A417V	-	-	Escherichia coli	aztreonamceftazidime avibactamcefiderocol	Reslit	Candidate
ftsI	A419G	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI Penicillin-binding protein 3	A437S	GCA->TCA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillincefotaximepenicillin+1 more	Reference Gene CatalogReslit	Confirmed
ftsI	A454V	-	penicillin-binding protein PBP3 FtsI	Pseudomonas aeruginosa	carbapenems	Reference Gene Catalog	Established
ftsI	A498T	-	penicillin-binding protein PBP3 FtsI	Escherichia coli	cephalosporins	Reference Gene Catalog	Established
ftsI Penicillin-binding protein 3	A502S	-	-	-	ampicillincefotaxime	Reslit	Candidate
ftsI Penicillin-binding protein 3	A502T	GCA->ACA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillincefotaximepenicillin+1 more	Reference Gene CatalogReslit	Confirmed
ftsI penicillin-binding protein 3	A502V	GCA->GTA	-	Haemophilus influenzae	ampicillinamoxicillincefotaxime+2 more	Reslit	Supported
ftsI penicillin-binding protein	A515V	-	increased binding affinity and sequestration of meropenem, penicillin-binding protein PBP3 FtsI	Acinetobacter baumannii	meropenemcarbapenemssulbactam durlobactam	Reference Gene CatalogReslit	Confirmed
ftsI Penicillin-binding protein 3	A530S	GCA->TCA	penicillin-binding protein PBP3 FtsI	Haemophilus influenzae	ampicillincefotaximepenicillin+2 more	Reference Gene CatalogReslit	Confirmed