Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
graSR two-component regulatory system | L26F | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
graSR two-component system | N197S | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
graSR two-component system | T136I | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
graSR two-component regulatory system | T224I | - | - | Staphylococcus aureus | vancomycin | Reslit | Candidate |
grcC1 polyprenyl diphosphate synthetase | A132V | - | reduced cell wall permeability | Mycobacterium marinum, Mycobacterium abscessus, Mycobacterium smegmatis | linezolidclarithromycinvancomycin+5 more | Reslit | Candidate |
grlA DNA gyrase subunit A | - | - | Staphylococcus aureus | ciprofloxacin | Reslit | Candidate | |
grlA DNA gyrase subunit A | - | - | Staphylococcus aureus | ciprofloxacin | Reslit | Candidate | |
grlA topoisomerase IV A subunit | A116E | - | mutations result in the synthesis of proteins with reduced susceptibility or insensitivity to fluoroquinolones, Target modification | Staphylococcus aureus | quinolonesfluoroquinolonesciprofloxacin+2 more | ResFinder DatabaseReslit | Confirmed |
grlA topoisomerase IV A subunit | A116P | - | Staphylococcus aureus | quinolonesciprofloxacin | Reslit | Supported | |
grlA DNA topoisomerase IV subunit A | A116V | - | - | Staphylococcus aureus | fluoroquinolones | Reslit | Candidate |
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