Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	D81N	-	single resistance variant, DNA gyrase subunit A GyrA	Mycoplasma agalactiae, Clostridioides difficile	enrofloxacinfluoroquinolonesquinolones	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase subunit A	D82A	-	-	Escherichia coli	quinolonesfluoroquinolones	Reslit	Candidate
gyrA DNA gyrase subunit A	D82G	-	Target modification, DNA gyrase subunit A GyrA	Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, Salmonella enterica	ciprofloxacinnalidixic acidfluoroquinolones+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D82N	-	Target modification, DNA gyrase subunit A GyrA	Salmonella enterica	nalidixic acidciprofloxacinfluoroquinolones+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D83N	-	-	Salmonella enterica	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	D83Y	-	-	Escherichia coli	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	D847N	-	-	Yersinia enterocolitica	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase A	D84N	-	-	Staphylococcus agnetis, Staphylococcus chromogenes, Staphylococcus arlettae, Staphylococcus lentus, Staphylococcus simulans	ciprofloxacin	Reslit	Candidate
gyrA	D85Y	-	Target modification, DNA gyrase subunit A GyrA	Campylobacter jejuni, Campylobacter coli	nalidixic acidciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA DNA gyrase subunit A	D86N	G257A	-	Helicobacter pylori	fluoroquinoloneslevofloxacinciprofloxacin	Reslit	Supported