Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA	D90A	-	Target modification, DNA gyrase subunit A GyrA	Mycobacterium tuberculosis, Campylobacter jejuni, Campylobacter coli	levofloxacinmoxifloxacinnalidixic acid+2 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D90G	-	single resistance variant	Mycobacterium tuberculosis, Bartonella bacilliformis	ofloxacinmoxifloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D90N	G269A	mutations in the DNA gyrase A (GyrA) region at multiple positions, Target modification, DNA gyrase subunit A GyrA	Campylobacter jejuni, Mycobacterium tuberculosis, Campylobacter coli	ciprofloxacinnalidixic acidquinolones+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	D90T	-	Target modification, DNA gyrase subunit A GyrA	Campylobacter jejuni, Campylobacter coli	nalidixic acidciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA DNA gyrase subunit A	D90Y	G269C	DNA gyrase subunit A GyrA	Campylobacter jejuni, Campylobacter coli	ciprofloxacinnalidixic acidfluoroquinolones+1 more	Reference Gene CatalogReslit	Confirmed
gyrA DNA gyrase subunit A	D91A	-	-	Corynebacterium spp., Corynebacterium urealyticum, Helicobacter pylori	fluoroquinolonesciprofloxacinlevofloxacin+1 more	Reslit	Supported
gyrA DNA gyrase subunit A	D91G	G273C	single resistance variant, multiple resistance variants, DNA gyrase subunit A GyrA	Helicobacter pylori, Corynebacterium spp.	levofloxacinmoxifloxacinciprofloxacin+3 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase A	D91H	-	single resistance variant	Helicobacter pylori	levofloxacinfluoroquinolones	Card DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	D91N	G272A G273A	multiple resistance variants, single resistance variant, DNA gyrase subunit A GyrA	Helicobacter pylori, Campylobacter fetus	levofloxacinmoxifloxacinciprofloxacin+4 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrA DNA gyrase subunit A	D91Y	G271T	confer resistance to LVX, single resistance variant, multiple resistance variants, DNA gyrase subunit A GyrA	Corynebacterium striatum, Helicobacter pylori, Corynebacterium spp., Corynebacterium jeikeium, Corynebacterium urealyticum, Campylobacter fetus	ciprofloxacinlevofloxacinmoxifloxacin+4 more	Card DatabaseReference Gene CatalogReslit	Confirmed