Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrA DNA gyrase subunit A	G75S	-	-	E. coli	ciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit	G79A	-	-	Streptococcus pneumoniae	fluoroquinolones	Reslit	Candidate
gyrA	G79C	-	single resistance variant, DNA gyrase subunit A GyrA	Acinetobacter baumannii	fluoroquinolonesquinolones	Card DatabaseReference Gene Catalog	Confirmed
gyrA	G80N	-	single resistance variant	Capnocytophaga gingivalis	fluoroquinolones	Card Database	Established
gyrA DNA gyrase A subunit	G81A	-	-	Ehrlichia chaffeensis, Ehrlichia canis, Mycoplasma hyopneumoniae	fluoroquinolonesciprofloxacinnalidixic acid+2 more	Reslit	Supported
gyrA DNA gyrase A subunit	G81C	G243T	confers resistance, disruption of the water-magnesium ion bridge, resists EDTA-mediated reversal, Target modification, single resistance variant, DNA gyrase subunit A GyrA	Staphylococcus aureus, Escherichia coli, Clostridium perfringens, Salmonella typhimurium, Yersinia pestis, E. coli, Klebsiella pneumoniae, Mycobacterium smegmatis, Salmonella enterica, Burkholderia pseudomallei, Pseudomonas aeruginosa	fluoroquinolonesquinolonesciprofloxacin+5 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA DNA gyrase subunit A	G81D	-	reduced susceptibility to ciprofloxacin, Target modification, single resistance variant, DNA gyrase subunit A GyrA	Salmonella Typhimurium, Salmonella Enteritidis, Pseudomonas aeruginosa, Escherichia coli, Salmonella enterica, Elizabethkingia anophelis, Burkholderia dolosa	ciprofloxacinfluoroquinoloneslevofloxacin+2 more	Card DatabaseReference Gene CatalogResFinder DatabaseReslit	Confirmed
gyrA	G81H	-	Target modification, DNA gyrase subunit A GyrA	Salmonella enterica	nalidixic acidciprofloxacinquinolones	Reference Gene CatalogResFinder Database	Confirmed
gyrA DNA gyrase subunit A	G81R	-	-	Staphylococcus hominis	fluoroquinolonesoxacillinciprofloxacin	Reslit	Candidate
gyrA DNA gyrase subunit A	G81S	-	Target modification, DNA gyrase subunit A GyrA	Acinetobacter baumannii, Salmonella enterica	ciprofloxacinlevofloxacinnalidixic acid+1 more	Reference Gene CatalogResFinder DatabaseReslit	Confirmed