Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrA DNA gyrase subunit A | G87D | - | disruption of the water-magnesium ion bridge | Escherichia coli | ciprofloxacin | Reslit | Candidate |
gyrA DNA gyrase subunit A | G87G | - | - | Klebsiella pneumoniae | fluoroquinolones | Reslit | Candidate |
gyrA DNA gyrase subunit A | G87N | - | - | Klebsiella pneumoniae | fluoroquinolones | Reslit | Candidate |
gyrA DNA gyrase subunit A | G882S | - | - | Acinetobacter baumannii | fluoroquinolones | Reslit | Candidate |
gyrA DNA gyrase subunit A | G88A | - | single resistance variant | Mycobacterium tuberculosis | fluoroquinolonesmoxifloxacinlevofloxacin+2 more | Card DatabaseResFinder DatabaseReslit | Confirmed |
gyrA DNA gyrase subunit A | G88C | single resistance variant | Mycobacterium smegmatis, Mycobacterium tuberculosis | ciprofloxacinlevofloxacinmoxifloxacin+4 more | Card DatabaseResFinder DatabaseReslit | Confirmed | |
gyrA DNA gyrase subunit A | G88D | - | - | Mycobacterium aurum | levofloxacin | Reslit | Candidate |
gyrA DNA gyrase subunit A | G88R | - | - | Mycobacterium tuberculosis | ofloxacin | Reslit | Candidate |
gyrA DNA gyrase subunit A | G89A | - | - | Mycobacterium leprae | ofloxacin | Reslit | Candidate |
gyrA DNA gyrase subunit A | G89C | - | - | Mycobacterium smegmatis, Mycobacterium leprae | fluoroquinolonesofloxacin | Reslit | Supported |
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