Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrA DNA gyrase subunit A | T665S | - | increased resistance to FQs | Campylobacter jejuni | ciprofloxacin | Reslit | Candidate |
gyrA DNA gyrase A subunit | T678A | - | - | Staphylococcus pseudintermedius | enrofloxacin | Reslit | Candidate |
gyrA DNA gyrase subunit A | T700N | - | - | - | fluoroquinolones | Reslit | Candidate |
gyrA DNA gyrase subunit A | T72C | - | - | - | ciprofloxacin | Reslit | Candidate |
gyrA DNA gyrase subunit A | T80A | - | single resistance variant | Mycobacterium tuberculosis | fluoroquinolonesquinolones | Card DatabaseResFinder DatabaseReslit | Confirmed |
gyrA DNA gyrase subunit A | T80I | decreased affinity for ciprofloxacin | Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Campylobacter, Neisseria gonorrhoeae, Neisseria meningitidis | fluoroquinolonesciprofloxacin | Reslit | Candidate | |
gyrA DNA gyrase subunit A | T81I | - | Campylobacter jejuni, Campylobacter coli, Streptococcus pneumoniae | quinoloneslevofloxacin | Reslit | Candidate | |
gyrA DNA gyrase subunit A | T828N | - | - | - | fluoroquinolones | Reslit | Candidate |
gyrA DNA gyrase subunit A | T829A | - | - | - | fluoroquinolones | Reslit | Candidate |
gyrA DNA gyrase | T82A | - | multiple resistance variants, single resistance variant, DNA gyrase subunit A GyrA | Clostridioides difficile | ciprofloxacinfluoroquinolonesquinolones | Card DatabaseReference Gene CatalogReslit | Confirmed |
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