Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB DNA gyrase subunit B | E466V | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Salmonella enterica, Clostridium ljungdahlii, Clostridioides difficile | fluoroquinolonesciprofloxacinquinolones | Card DatabaseReference Gene CatalogReslit | Confirmed |
gyrB DNA gyrase subunit B | E468D | - | DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Pseudomonas aeruginosa, Klebsiella pneumoniae, Pseudomonas putida | levofloxacinciprofloxacinfluoroquinolones+4 more | Reference Gene CatalogReslit | Confirmed |
| E468H | - | DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Pseudomonas aeruginosa | quinolones | Reference Gene Catalog | Established | |
gyrB DNA gyrase subunit B | E468Q | - | - | Salmonella enterica | ciprofloxacin | Reslit | Candidate |
gyrB DNA topoisomerase (ATP-hydrolyzing) subunit | E469D | - | - | Salmonella Typhimurium, Pseudomonas putida, Haemophilus influenzae | fluoroquinolones | Reslit | Supported |
gyrB DNA gyrase subunit B | E471K | - | - | fluoroquinolones | Reslit | Candidate | |
gyrB DNA gyrase subunit B | E472G | - | - | Haemophilus influenzae | levofloxacinciprofloxacinmoxifloxacin+1 more | Reslit | Candidate |
gyrB DNA gyrase subunit B | E472V | - | - | Escherichia coli | ciprofloxacinfluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase B subunit | E474K | - | - | Streptococcus pneumoniae | ofloxacinlevofloxacingemifloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | E475K | - | - | Bartonella bacilliformis | ciprofloxacin | Reslit | Candidate |
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