Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| E502Q | - | single resistance variant | Ureaplasma urealyticum | fluoroquinolones | Card Database | Established | |
| E504V | - | single resistance variant | Mycobacterium leprae | fluoroquinolones | Card Database | Established | |
gyrB DNA gyrase subunit B | E512D | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | Candidate | |
gyrB DNA gyrase subunit B | E540D | confers resistance to moxifloxacin, confers resistance to quinolones | Mycobacterium tuberculosis | ofloxacinfluoroquinolonesmoxifloxacin+4 more | Reslit | Supported | |
gyrB DNA gyrase B subunit | E540V | - | confers resistance to all four fluoroquinolones tested | Mycobacterium tuberculosis | fluoroquinolonesciprofloxacinlevofloxacin+6 more | Reslit | Supported |
gyrB DNA gyrase subunit B | E594D | - | - | - | moxifloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | E641K | - | - | - | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | E679D | - | - | Acinetobacter baumannii | ciprofloxacingemifloxacinlevofloxacin+2 more | Reslit | Candidate |
gyrB DNA gyrase subunit B | E747K | - | - | Francisella tularensis | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | E793K | - | Escherichia coli | fluoroquinolones | Reslit | Candidate |
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