Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB DNA gyrase subunit B | K447E | - | Target modification, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | E. coli, Escherichia coli | quinolonesnalidixic acid | Reference Gene CatalogResFinder DatabaseReslit | Confirmed |
gyrB DNA gyrase subunit B | K450I | - | - | Neisseria mucosa | zoliflodacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | K450N | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Neisseria gonorrhoeae | zoliflodacin | Card DatabaseReference Gene CatalogReslit | Confirmed |
gyrB DNA gyrase subunit B | K450T | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Neisseria gonorrhoeae | zoliflodacin | Card DatabaseReference Gene CatalogReslit | Confirmed |
gyrB DNA gyrase subunit B | K473R | - | - | Chryseobacterium indologenes | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | K639N | - | - | - | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | K679R | - | - | Mycobacterium tuberculosis | moxifloxacin | Reslit | Candidate |
gyrB DNA gyrase subunit B | L249E | - | - | Escherichia coli | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | L406I | - | - | Clostridioides difficile | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase B subunit | L422P | - | - | Escherichia coli | ciprofloxacin | Reslit | Candidate |
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