Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
gyrB DNA gyrase subunit B | N499I | - | - | Mycobacterium tuberculosis | ofloxacin | Reslit | Candidate |
| N499K | - | single resistance variant | Mycobacterium tuberculosis | fluoroquinolones | Card DatabaseResFinder Database | Confirmed | |
gyrB DNA gyrase subunit B | N499S | - | - | - | ofloxacinmoxifloxacinciprofloxacin+1 more | Reslit | Candidate |
gyrB DNA gyrase subunit B | N499T | - | single resistance variant | Mycobacterium tuberculosis | fluoroquinolonesofloxacinmoxifloxacin+2 more | Card DatabaseResFinder DatabaseReslit | Confirmed |
gyrB DNA gyrase subunit B | N499Y | - | - | Mycobacterium tuberculosis | ofloxacinmoxifloxacinciprofloxacin+2 more | ResFinder DatabaseReslit | Confirmed |
| N502D | - | single resistance variant | Mycobacterium leprae | fluoroquinolones | Card Database | Established | |
gyrB DNA gyrase subunit B | N510D | - | resistance | Mycobacterium tuberculosis | quinolonesfluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | N538D | confers resistance to all four fluoroquinolones tested, resistance, confers resistance to quinolones, multiple resistance variants | Mycobacterium tuberculosis | fluoroquinolonesciprofloxacinofloxacin+4 more | Card DatabaseReslit | Confirmed | |
gyrB DNA gyrase subunit B | N538I | - | - | Mycobacterium tuberculosis | fluoroquinolones | Reslit | Candidate |
gyrB DNA gyrase subunit B | N538K | - | confers resistance to moxifloxacin | Mycobacterium tuberculosis | moxifloxacin | Reslit | Candidate |
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