Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| R136C | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R136E | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R136G | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R136H | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R136I | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R136L | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R136S | - | single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Escherichia coli | aminocoumarin | Card DatabaseReference Gene Catalog | Confirmed | |
| R138L | - | - | Pseudomonas aeruginosa | ciprofloxacin | Reslit | Candidate | |
| R143I | - | DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Staphylococcus aureus | aminocoumarin | Reference Gene Catalog | Established | |
| R143S | - | DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB | Staphylococcus aureus | aminocoumarin | Reference Gene Catalog | Established |
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