Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
gyrB	S127L	-	DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Staphylococcus aureus	aminocoumarin	Reference Gene Catalog	Established
gyrB	S128L	-	single resistance variant	Staphylococcus aureus	aminocoumarin	Card Database	Established
gyrB DNA gyrase subunit B	S279G	-	-	Helicobacter pylori	levofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S302A	TCA->GCC	-	Mycoplasma hominis	ofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S361P	-	-	E. coli	ciprofloxacin	Reslit	Candidate
gyrB DNA gyrase subunit B	S366A	TCA->GCC	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium ljungdahlii, Clostridioides difficile	fluoroquinolonesquinolones	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S366V	-	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium difficile, Clostridium ljungdahlii, Clostridioides difficile	fluoroquinolonesciprofloxacinmoxifloxacin+1 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S416A	-	single resistance variant, DNA topoisomerase (ATP-hydrolyzing) subunit B GyrB	Clostridium difficile, Clostridium ljungdahlii, Clostridioides difficile	moxifloxacinciprofloxacingatifloxacin+3 more	Card DatabaseReference Gene CatalogReslit	Confirmed
gyrB DNA gyrase subunit B	S416Y	C1247A	-	Mycoplasma synoviae	fluoroquinolones	Reslit	Candidate
gyrB DNA gyrase subunit B	S417N	-	-	Mycoplasma synoviae	enrofloxacin	Reslit	Candidate