Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| E607A | - | single resistance variant | Mycobacterium tuberculosis | isoniazidprothionamide | Card Database | Established | |
katG catalase-peroxidase | E607K | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Candidate |
katG catalase-peroxidase | F129L | - | - | - | isoniazid | Reslit | Candidate |
katG ketoacyl-ACP synthase III | F183L | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
katG catalase-peroxidase | F185L | - | - | - | isoniazid | Reslit | Candidate |
katG catalase-peroxidase | F483L | - | single resistance variant | Mycobacterium smegmatis, Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
katG catalase-peroxidase | G105R | - | - | Mycobacterium tuberculosis | isoniazid | Reslit | Candidate |
| G111S | - | single resistance variant | Mycobacterium tuberculosis | isoniazidprothionamide | Card Database | Established | |
| G123E | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card Database | Established | |
katG KatG enzyme, a catalase-peroxidase involved in the activation of isoniazid (INH) | G124S | - | single resistance variant | Mycobacterium tuberculosis | isoniazid | Card DatabaseReslit | Confirmed |
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