Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| blaROB-1 | A237T | - | increased resistance to extended-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations | Escherichia coli | cefotaxime|amoxicillin-clavulanate | Reslit | Candidate |
| blaROB-1 | L169S | - | increased resistance to extended-spectrum cephalosporins | Escherichia coli | cefotaxime | Reslit | Candidate |
| blaROB-1 | R164W | - | increased resistance to extended-spectrum cephalosporins and β-lactam-β-lactamase inhibitor combinations | Escherichia coli | cefotaxime|amoxicillin-clavulanate | Reslit | Candidate |
| blaSHV-1 | - | - | Klebsiella pneumoniae | ceftazidime|piperacillin-tazobactam | Reslit | Candidate | |
| blaSHV-1 | D104K | - | - | Escherichia coli | cefotaxime|ceftazidime | Reslit | Candidate |
| blaSHV-1 | D104R | - | - | Escherichia coli | cefotaxime|ceftazidime | Reslit | Candidate |
| blaSHV-1 | G238A | - | conferred the most resistance to penicillins and cephalosporins | Escherichia coli | penicillins|cephalosporins | Reslit | Candidate |
| blaSHV-1 | G238C | - | demonstrated lower levels of resistance | Escherichia coli | penicillins|cephalosporins | Reslit | Candidate |
| blaSHV-1 | G238D | - | demonstrated lower levels of resistance | Escherichia coli | penicillins|cephalosporins | Reslit | Candidate |
| blaSHV-1 | G238P | - | demonstrated lower levels of resistance | Escherichia coli | penicillins|cephalosporins | Reslit | Candidate |
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