Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
alr alanine racemase | R243S | - | destabilizing | Mycobacterium tuberculosis | cycloserine | Reslit | Candidate |
alr D-alanine racemase | S22L | - | - | cycloserine | Reslit | Supported | |
alr Alanine racemase | T20M | - | destabilizing | Mycobacterium tuberculosis | cycloserine | Reslit | Candidate |
alr alanine racemase | Y388C | - | - | - | cycloserine | Reslit | Candidate |
alr Alanine racemase | Y388D | - | - | - | cycloserine | Reslit | Supported |
amgS histidine kinase sensor | A203V | - | mutations in the linker domain of AmgS, the closest Escherichia coli homolog of AmgS, often cause activation of the kinase sensor | Pseudomonas aeruginosa | aminoglycosides | Reslit | Candidate |
amgS sensor kinase | C28A | - | - | Pseudomonas aeruginosa | tobramycin | Reslit | Candidate |
amgS putative ABC transporter | E108Q | - | - | Pseudomonas aeruginosa | amikacin | Reslit | Candidate |
amgS histidine kinase sensor | P116L | - | mutations in the sensor domain of AmgS, where mutations involved in aminoglycoside resistance have been previously described | Pseudomonas aeruginosa | aminoglycosides | Reslit | Candidate |
| P381S | - | two-component system sensor histidine kinase AmgS | Pseudomonas aeruginosa | carbapenems | Reference Gene Catalog | Established |
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