Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ampC β-lactamase | V213A | - | increased β-lactamase hydrolysis activity | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC beta-lactamase | V239A | - | - | Pseudomonas aeruginosa | aztreonam | Reslit | Candidate |
ampC Cephalosporin-hydrolyzing class C beta-lactamase | V318A | - | - | Enterobacter hormaechei | cefiderocol | Reslit | Candidate |
ampC β-lactamase | V329I | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC cephalosporinase | V356I | - | - | Pseudomonas aeruginosa | ceftazidimecefepimeticarcillin+2 more | Reslit | Candidate |
ampD Regulatory gene for AmpC beta-lactamase | - | - | Pseudomonas aeruginosa | ceftazidime avibactamceftolozane tazobactam | Reslit | Candidate | |
ampD AmpC cephalosporinase regulator | A134V | - | - | - | ticarcillinpiperacillincefepime+2 more | Reslit | Candidate |
| A18E | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Burkholderia cenocepacia | cephalosporins | Reference Gene Catalog | Established | |
ampD peptidoglycan hydrolase | C110G | - | - | - | fluoroquinolones | Reslit | Candidate |
ampD1 peptidoglycan-recycling amidase | G148A | - | nonfunctional | Pseudomonas aeruginosa | ceftazidime | Reslit | Candidate |
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