Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
ampC beta-lactamase | S273R | - | - | Escherichia coli | cefoxitin | Reslit | Candidate |
ampC β-lactamase | S287C | - | increased resistance | E. coli | cefepime | Reslit | Candidate |
ampC β-lactamase | S287N | - | increased resistance | E. coli | cefepime | Reslit | Candidate |
ampC β-lactamase | S90A | - | The nonphosphorylatable mutant S90A was found to be more resistant to imipenem | Acinetobacter baumannii | imipenem | Reslit | Candidate |
ampC β-lactamase | S90D | - | The phosphorylation-simulated mutant S90D was sensitive to imipenem | Acinetobacter baumannii | imipenem | Reslit | Candidate |
ampC beta-lactamase | T105A | - | more efficient carbapenem and cefepime hydrolysis | Pseudomonas aeruginosa | imipenemceftazidimecefepime+1 more | Reslit | Candidate |
ampC beta-lactamase | T70I | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC β-lactamase | T79A | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
ampC beta-lactamase | T96I | - | reduced susceptibility to inhibition by avibactam | Pseudomonas aeruginosa | ceftolozaneceftazidimeavibactam+2 more | Reslit | Supported |
ampC β-lactamase | V179L | - | - | Pseudomonas aeruginosa | ceftolozane tazobactam | Reslit | Candidate |
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