Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
pbp1a penicillin-binding protein 1A | T574N | - | reduced affinity for β-lactam antibiotics | Streptococcus pneumoniae | penicillinmeropenem | Reslit | Candidate |
pbp1a penicillin-binding protein 1A | T593A | - | Helicobacter pylori | amoxicillin | Reslit | Supported | |
pbp1a penicillin-binding protein 1A | T593P | - | - | Helicobacter pylori | amoxicillin | Reslit | Candidate |
pbp1a penicillin-binding protein 1A | T593S | - | - | Helicobacter pylori | amoxicillin | Reslit | Candidate |
pbp1a penicillin-binding protein | T612L | - | - | - | meropenem | Reslit | Candidate |
pbp1a penicillin-binding protein | T612Y | - | - | - | meropenem | Reslit | Candidate |
pbp1a penicillin-binding protein 1a | T636A | - | Large decrease in stability | Acinetobacter baumannii | carbapenems | Reslit | Candidate |
pbp1a penicillin-binding protein 1A | T701P | - | - | Streptococcus agalactiae | penicillincefotaxime | Reslit | Candidate |
pbp1a penicillin-binding protein 1A | V16I | - | - | Helicobacter pylori | ampicillin | Reslit | Candidate |
pbp1a penicillin-binding protein 1A | V346L | - | - | Helicobacter pylori | amoxicillin | Reslit | Candidate |
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