Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2 penicillin-binding protein 2	P825A	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
pbp2 penicillin-binding protein 2	R262C	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
pbp2 penicillin-binding protein 2	S494H	-	single resistance variant	Helicobacter pylori	amoxicillin	Card DatabaseReslit	Confirmed
pbp2	S569A	-	Target modification, penicillin-binding protein PBP2	Staphylococcus aureus	cefoxitincephalosporins	Reference Gene CatalogResFinder Database	Confirmed
pbp2 penicillin-binding protein 2	T31M	-	-	Staphylococcus aureus	oxacillincefoxitinpenicillin	Reslit	Candidate
pbp2 penicillin-binding protein 2	T439V	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
pbp2 penicillin-binding protein 2	T483S	-	lower affinity for ceftriaxone and restrict conformational changes that normally accompany acylation, single resistance variant	Neisseria gonorrhoeae	ceftazidimeceftriaxonebeta lactams	Card DatabaseReslit	Confirmed
pbp2 penicillin-binding protein 2	T489E	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate
pbp2 penicillin-binding protein 2	T534A	-	-	-	ceftriaxonecefixime	Reslit	Candidate
pbp2 penicillin-binding protein 2	T691A	-	-	Staphylococcus aureus	vancomycin	Reslit	Candidate