Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x penicillin-binding protein	G422D	-	reduced amount of PBP2x	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	H394L	-	-	Streptococcus pneumoniae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	H438Y	-	substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	I343V	-	-	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2X	I366M	-	-	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	I371T	-	decreased the affinity of the protein for a β-lactam, single resistance variant	Streptococcus pneumoniae, Streptococcus mitis	penicillincefotaximeamoxicillin	Card DatabaseReslit	Confirmed
pbp2x penicillin-binding protein 2X	I377V	-	substitutions in PBP2X are associated with penicillin non-susceptibility	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	L364F	-	decreased the affinity of the protein for a β-lactam	Streptococcus pneumoniae, Streptococcus mitis	penicillincefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	L382I	-	-	Enterococcus cecorum	amoxicillintrimethoprim sulfamethoxazoleampicillin+1 more	Reslit	Candidate
pbp2x penicillin-binding protein	L403F	-	reduced amount of PBP2x	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate