Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
pbp2x penicillin-binding protein 2x	N605T	-	single resistance variant	Streptococcus pneumoniae, Streptococcus mitis	penicillincefotaximeamoxicillin	Card DatabaseReslit	Confirmed
pbp2x penicillin-binding protein 2x	P160S	-	-	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	P410L	-	-	Streptococcus agalactiae	penicillin	Reslit	Candidate
pbp2x	P601L	-	decreased in vitro susceptibility to β-lactam antibiotics, significantly decreases susceptibility to beta-lactam antibiotics in vitro and increases GAS fitness in vivo, reduced β-lactam susceptibility, single resistance variant, penicillin-binding protein 2X	Streptococcus pyogenes	beta lactamspenicillinampicillin+6 more	Card DatabaseReference Gene CatalogReslit	Confirmed
pbp2x penicillin-binding protein	Q281L	-	-	Streptococcus pneumoniae	cefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q366K	-	-	Enterococcus cecorum	ampicillinceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q405E	-	-	Streptococcus suis	amoxicillin clavulanic acidampicillin	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q405K	-	-	Streptococcus pneumoniae, Streptococcus mitis	penicillincefotaxime	Reslit	Candidate
pbp2x penicillin-binding protein 2x	Q453H	-	-	Streptococcus suis	ceftiofur	Reslit	Candidate
pbp2x penicillin-binding protein	Q548E	-	confers resistance	Streptococcus gordonii	penicillin	Reslit	Candidate