Browse AMR Mutations
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
Explore antimicrobial resistance mutations from the literature
| Gene | Protein Change | Nucleotide Change | Mechanism | Organism | Resistance To | Database | Validation Status |
|---|---|---|---|---|---|---|---|
| ampD | P46T | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Burkholderia cenocepacia | CEPHALOSPORIN | Reference Gene Catalog | Established |
| ampD | Q155Ter | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Pseudomonas aeruginosa |
CEPHALOSPORIN |
Reference Gene Catalog |
| Established |
| ampD | Q44Ter | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Pseudomonas aeruginosa | CEPHALOSPORIN | Reference Gene Catalog | Established |
| ampD | Q88L | - | - | - | Ceftazidime | Reslit | Candidate |
| ampD | R161H | - | The Arg161His substitution was predicted to weaken ligand binding, likely affecting the positioning of the ligand in the active site. | Klebsiella aerogenes | Ertapenem|Imipenem|Meropenem | Reslit | Candidate |
| ampD | R167S | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Burkholderia cenocepacia | CEPHALOSPORIN | Reference Gene Catalog | Established |
| ampD | R22H | - | - | Cefotaxime|Ceftazidime|Cefepime | Reslit | Candidate |
| ampD | R345Q | - | - | Pseudomonas aeruginosa | Cephalosporin|Penicillin | Reslit | Candidate |
| ampD | R79G | - | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD | Burkholderia cenocepacia | CEPHALOSPORIN | Reference Gene Catalog | Established |
| ampD | R93P | - | - | Cefotaxime|Ceftazidime|Cefepime | Reslit | Candidate |
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