Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
penA β-lactamase	D179T	-	-	Burkholderia thailandensis	ceftazidime	Reslit	Candidate
penA penicillin-binding protein 2	D346A	-	lowered the acylation rate of penicillin G by 5-fold	Neisseria gonorrhoeae	penicillin	Reslit	Candidate
penA	D346DD	-	penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae	beta lactams	Reference Gene Catalog	Established
penA penicillin-binding protein 2 (PBP2)	D511V	-	-	Neisseria meningitidis	penicillincefotaxime	Reslit	Candidate
penA penicillin-binding protein 2 (PBP2)	D86N	-	-	Neisseria gonorrhoeae	ciprofloxacin	Reslit	Candidate
penA penicillin-binding protein 2 (PBP2)	E101D	-	-	Neisseria gonorrhoeae	cefixime	Reslit	Candidate
penA β-lactamase	E166K	-	-	Burkholderia thailandensis	ceftazidime	Reslit	Candidate
penA penicillin-binding protein 2	E285D	-	-	Neisseria gonorrhoeae	ceftriaxone	Reslit	Candidate
penA penicillin-binding protein 2 (PBP-2)	E377K	-	-	Neisseria gonorrhoeae	cephalosporins	Reslit	Candidate
penA Penicillin-Binding Protein 2	F504L	T1512C	reduced reactivity for β-lactams, penicillin-binding protein PBP2 PenA	Neisseria gonorrhoeae, Neisseria meningitidis	ceftriaxonecefiximepenicillin+3 more	Reference Gene CatalogReslit	Confirmed