Browse AMR Mutations

Explore antimicrobial resistance mutations from the literature

Gene	Protein Change	Nucleotide Change	Mechanism	Organism	Resistance To	Database	Validation Status
ampG transmembrane protein	Q131H	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	ampicillin	Reslit	Candidate
ampG transmembrane protein	Q131P	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	ampicillin	Reslit	Candidate
ampG transmembrane protein	Q131R	-	loss of function	Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, Acinetobacter baumannii	ampicillin	Reslit	Candidate
ampG transmembrane protein functioning as a specific permease to transport 1,6-GldNAc-anhydro-MurNAc and 1,6-GldNAc-anhydro-MurNAc peptide	W90R	-	no significant change	Pseudomonas aeruginosa	ampicillin	Reslit	Candidate
ampG transmembrane protein functioning as a specific permease to transport 1,6-GldNAc-anhydro-MurNAc and 1,6-GldNAc-anhydro-MurNAc peptide	W90S	-	no significant change	Pseudomonas aeruginosa	ampicillin	Reslit	Candidate
ampR	-	G-98A	-	Pseudomonas aeruginosa	imipenemampicillin	Reslit	Candidate
ampR transcriptional regulator	*297Y	-	-	Pseudomonas aeruginosa	piperacillin	Reslit	Candidate
ampR transcriptional regulator	D135A	-	activator	Escherichia coli	cephalosporins	Reslit	Candidate
ampR transcriptional regulator	D135G	-	single resistance variant, transcriptional regulator AmpR	Pseudomonas aeruginosa, Enterococcus faecium	ceftolozanetazobactambeta lactams+3 more	Card DatabaseReference Gene CatalogReslit	Confirmed
ampR transcriptional regulator	D135N	GAC->AAC	upregulates AmpC expression, single resistance variant, transcriptional regulator AmpR	Pseudomonas aeruginosa	ceftolozanetazobactamciprofloxacin+5 more	Card DatabaseReference Gene CatalogReslit	Confirmed